diff --git a/homeassistant/components/influxdb/__init__.py b/homeassistant/components/influxdb/__init__.py
index bcab3ad32380..f4aad5a65b3c 100644
--- a/homeassistant/components/influxdb/__init__.py
+++ b/homeassistant/components/influxdb/__init__.py
@@ -209,10 +209,19 @@ CONFIG_SCHEMA = probatio.Schema(
 )
 
 
+def _single_line(value: str) -> str:
+    """Return the value with its line breaks replaced by spaces.
+
+    Line protocol has no escape for a line break, in a string field it ends
+    the point, and the escape the clients use for tags is not one either.
+    """
+    return " ".join(value.splitlines())
+
+
 def _generate_event_to_json(conf: dict) -> Callable[[Event], dict[str, Any] | None]:
     """Build event to json converter and add to config."""
     entity_filter = convert_include_exclude_filter(conf)
-    tags = conf.get(CONF_TAGS)
+    tags = {key: _single_line(value) for key, value in conf[CONF_TAGS].items()}
     tags_attributes: list[str] = conf[CONF_TAGS_ATTRIBUTES]
     default_measurement = conf.get(CONF_DEFAULT_MEASUREMENT)
     measurement_attr: str = conf[CONF_MEASUREMENT_ATTR]
@@ -276,6 +285,9 @@ def _generate_event_to_json(conf: dict) -> Callable[[Event], dict[str, Any] | No
                 else:
                     include_uom = measurement_attr != "unit_of_measurement"
 
+        if isinstance(measurement, str):
+            measurement = _single_line(measurement)
+
         json: dict[str, Any] = {
             INFLUX_CONF_MEASUREMENT: measurement,
             INFLUX_CONF_TAGS: {
@@ -286,7 +298,7 @@ def _generate_event_to_json(conf: dict) -> Callable[[Event], dict[str, Any] | No
             INFLUX_CONF_FIELDS: {},
         }
         if _include_state:
-            json[INFLUX_CONF_FIELDS][INFLUX_CONF_STATE] = state.state
+            json[INFLUX_CONF_FIELDS][INFLUX_CONF_STATE] = _single_line(state.state)
         if _include_value:
             json[INFLUX_CONF_FIELDS][INFLUX_CONF_VALUE] = _state_as_value
 
@@ -294,7 +306,9 @@ def _generate_event_to_json(conf: dict) -> Callable[[Event], dict[str, Any] | No
         ignore_attributes.update(global_ignore_attributes)
         for key, value in state.attributes.items():
             if key in tags_attributes:
-                json[INFLUX_CONF_TAGS][key] = value
+                json[INFLUX_CONF_TAGS][key] = (
+                    _single_line(value) if isinstance(value, str) else value
+                )
             elif (
                 (key != CONF_UNIT_OF_MEASUREMENT or include_uom)
                 and (key != "device_class" or include_dc)
@@ -311,7 +325,7 @@ def _generate_event_to_json(conf: dict) -> Callable[[Event], dict[str, Any] | No
                     json[INFLUX_CONF_FIELDS][key] = float(value)
                 except ValueError, TypeError:
                     new_key = f"{key}_str"
-                    new_value = str(value)
+                    new_value = _single_line(str(value))
                     json[INFLUX_CONF_FIELDS][new_key] = new_value
 
                     if RE_DIGIT_TAIL.match(new_value):
diff --git a/tests/components/influxdb/test_init.py b/tests/components/influxdb/test_init.py
index 0eface64cb7e..8d9ad5b4a571 100644
--- a/tests/components/influxdb/test_init.py
+++ b/tests/components/influxdb/test_init.py
@@ -1,6 +1,6 @@
 """The tests for the InfluxDB component."""
 
-from collections.abc import Generator
+from collections.abc import Callable, Generator
 from dataclasses import dataclass
 import datetime
 from http import HTTPStatus
@@ -621,6 +621,77 @@ async def test_event_listener(
         write_api.reset_mock()
 
 
+@pytest.mark.parametrize(
+    ("hass_config", "mock_client", "config_ext", "get_write_api", "get_mock_call"),
+    [
+        (
+            {
+                "influxdb": {
+                    "override_measurement": "state\nlog",
+                    "tags_attributes": ["room"],
+                    "tags": {"site": "first\nfloor"},
+                }
+            },
+            influxdb.DEFAULT_API_VERSION,
+            BASE_V1_CONFIG,
+            _get_write_api_mock_v1,
+            influxdb.DEFAULT_API_VERSION,
+        ),
+        (
+            {
+                "influxdb": {
+                    "override_measurement": "state\nlog",
+                    "tags_attributes": ["room"],
+                    "tags": {"site": "first\nfloor"},
+                }
+            },
+            influxdb.API_VERSION_2,
+            BASE_V2_CONFIG,
+            _get_write_api_mock_v2,
+            influxdb.API_VERSION_2,
+        ),
+    ],
+    indirect=["mock_client", "get_mock_call"],
+)
+async def test_event_listener_multiline_strings(
+    hass: HomeAssistant,
+    mock_client: MagicMock,
+    config_ext: dict[str, Any],
+    get_write_api: Callable[[MagicMock], MagicMock],
+    get_mock_call: Callable[..., Any],
+) -> None:
+    """Test line breaks in strings are replaced, line protocol has no escape for them."""
+    await _setup(hass, mock_client, config_ext, get_write_api)
+
+    hass.states.async_set(
+        "fake.entity_id",
+        "Avenida de Logroño, 50\n28002 Madrid\r\nEspaña",
+        {"address": "line one\nline two", "room": "living\nroom"},
+    )
+    await hass.async_block_till_done()
+    await async_wait_for_queue_to_process(hass)
+
+    body = [
+        {
+            "measurement": "state log",
+            "tags": {
+                "domain": "fake",
+                "entity_id": "entity_id",
+                "room": "living room",
+                "site": "first floor",
+            },
+            "time": ANY,
+            "fields": {
+                "state": "Avenida de Logroño, 50 28002 Madrid España",
+                "address_str": "line one line two",
+            },
+        }
+    ]
+    write_api = get_write_api(mock_client)
+    assert write_api.call_count == 1
+    assert write_api.call_args == get_mock_call(body)
+
+
 @pytest.mark.parametrize(
     ("hass_config", "mock_client", "config_ext", "get_write_api", "get_mock_call"),
     [