diff --git a/homeassistant/components/conversation/default_agent.py b/homeassistant/components/conversation/default_agent.py
index 3e7a4cc8e90a..a7fa22670d65 100644
--- a/homeassistant/components/conversation/default_agent.py
+++ b/homeassistant/components/conversation/default_agent.py
@@ -83,6 +83,7 @@ _LOGGER = logging.getLogger(__name__)
 
 _DEFAULT_ERROR_TEXT = "Sorry, I couldn't understand that"
 _ENTITY_REGISTRY_UPDATE_FIELDS = ["aliases", "name", "original_name"]
+_DEVICE_REGISTRY_UPDATE_FIELDS = ["name", "name_by_user"]
 
 _DEFAULT_EXPOSED_ATTRIBUTES = {"device_class"}
 
@@ -288,6 +289,15 @@ class DefaultAgent(ConversationEntity):
             field in event_data["changes"] for field in _ENTITY_REGISTRY_UPDATE_FIELDS
         )
 
+    @callback
+    def _filter_device_registry_changes(
+        self, event_data: dr.EventDeviceRegistryUpdatedData
+    ) -> bool:
+        """Filter device registry changed events."""
+        return event_data["action"] == "update" and any(
+            field in event_data["changes"] for field in _DEVICE_REGISTRY_UPDATE_FIELDS
+        )
+
     @callback
     def _filter_state_changes(self, event_data: EventStateChangedData) -> bool:
         """Filter state changed events."""
@@ -312,6 +322,11 @@ class DefaultAgent(ConversationEntity):
                 self._async_clear_slot_list,
                 event_filter=self._filter_entity_registry_changes,
             ),
+            self.hass.bus.async_listen(
+                dr.EVENT_DEVICE_REGISTRY_UPDATED,
+                self._async_clear_slot_list,
+                event_filter=self._filter_device_registry_changes,
+            ),
             self.hass.bus.async_listen(
                 EVENT_STATE_CHANGED,
                 self._async_clear_slot_list,
diff --git a/tests/components/conversation/test_default_agent.py b/tests/components/conversation/test_default_agent.py
index 3b852d7883fc..fcf3212f0608 100644
--- a/tests/components/conversation/test_default_agent.py
+++ b/tests/components/conversation/test_default_agent.py
@@ -492,6 +492,54 @@ async def test_duplicated_names_resolved_with_device_area(
         assert result.response.intent.slots.get("name", {}).get("text") == name
 
 
+@pytest.mark.usefixtures("init_components")
+async def test_device_rename_refreshes_slot_list(
+    hass: HomeAssistant,
+    device_registry: dr.DeviceRegistry,
+    entity_registry: er.EntityRegistry,
+) -> None:
+    """Test renaming a device makes the entity matchable by its new computed name."""
+    config_entry = MockConfigEntry()
+    config_entry.add_to_hass(hass)
+    device = device_registry.async_get_or_create(
+        config_entry_id=config_entry.entry_id,
+        connections=set(),
+        identifiers={("demo", "device-1")},
+        name="Kitchen",
+    )
+
+    light = entity_registry.async_get_or_create(
+        "light",
+        "demo",
+        "1234",
+        device_id=device.id,
+        has_entity_name=True,
+        original_name="Light",
+    )
+    hass.states.async_set(light.entity_id, "off")
+    expose_entity(hass, light.entity_id, True)
+
+    # Populate the slot list cache: the current computed name matches.
+    calls = async_mock_service(hass, "light", "turn_on")
+    result = await conversation.async_converse(
+        hass, "turn on Kitchen Light", None, Context(), None
+    )
+    assert result.response.response_type is intent.IntentResponseType.ACTION_DONE
+    assert len(calls) == 1
+
+    # Renaming the device changes the light's computed name to "Bedroom Light".
+    device_registry.async_update_device(device.id, name_by_user="Bedroom")
+    await hass.async_block_till_done()
+
+    # The new name is now matchable.
+    calls = async_mock_service(hass, "light", "turn_on")
+    result = await conversation.async_converse(
+        hass, "turn on Bedroom Light", None, Context(), None
+    )
+    assert result.response.response_type is intent.IntentResponseType.ACTION_DONE
+    assert len(calls) == 1
+
+
 @pytest.mark.usefixtures("init_components")
 async def test_trigger_sentences(hass: HomeAssistant) -> None:
     """Test registering/unregistering/matching a few trigger sentences."""