diff --git a/homeassistant/components/serial/manifest.json b/homeassistant/components/serial/manifest.json
index 9b55c513194d..97a3a1b48f36 100644
--- a/homeassistant/components/serial/manifest.json
+++ b/homeassistant/components/serial/manifest.json
@@ -4,5 +4,5 @@
   "codeowners": ["@fabaff"],
   "documentation": "https://www.home-assistant.io/integrations/serial",
   "iot_class": "local_polling",
-  "requirements": ["serialx==1.9.0"]
+  "requirements": ["serialx==1.10.0"]
 }
diff --git a/homeassistant/components/usb/manifest.json b/homeassistant/components/usb/manifest.json
index 205913f357f8..0c39ab2d7e19 100644
--- a/homeassistant/components/usb/manifest.json
+++ b/homeassistant/components/usb/manifest.json
@@ -8,5 +8,5 @@
   "integration_type": "system",
   "iot_class": "local_push",
   "quality_scale": "internal",
-  "requirements": ["aiousbwatcher==1.1.2", "serialx==1.9.0"]
+  "requirements": ["aiousbwatcher==1.1.2", "serialx==1.10.0"]
 }
diff --git a/homeassistant/package_constraints.txt b/homeassistant/package_constraints.txt
index df8a74a79225..3565573823b0 100644
--- a/homeassistant/package_constraints.txt
+++ b/homeassistant/package_constraints.txt
@@ -65,7 +65,7 @@ PyTurboJPEG==1.8.3
 PyYAML==6.0.3
 requests==2.34.2
 securetar==2026.4.1
-serialx==1.9.0
+serialx==1.10.0
 SQLAlchemy==2.0.52
 standard-aifc==3.13.0
 standard-telnetlib==3.13.0
diff --git a/requirements_all.txt b/requirements_all.txt
index 281a4ee2994b..f6971c689289 100644
--- a/requirements_all.txt
+++ b/requirements_all.txt
@@ -3057,7 +3057,7 @@ sentry-sdk==2.48.0
 
 # homeassistant.components.serial
 # homeassistant.components.usb
-serialx==1.9.0
+serialx==1.10.0
 
 # homeassistant.components.sfr_box
 sfrbox-api==0.1.1